Design for Social Impact [D4Si] – 2nd International Conference is a space for reflection on design for society. This biennial event brings together the work of researchers, academics, students, and designers from around the world. D4Si is centred on the field of Design, to promote an open, broad, and plural discussion across different areas of knowledge. By fostering multidisciplinary and interdisciplinary collaboration, the conference seeks to advance science and encourage holistic development. In the face of the growing complexity of the challenges that characterise contemporary society, designers must position themselves as an integral part of the solution, taking on an active role as agents of change. We believe in the contribution of research to society and therefore aim to offer a strong scientific programme that highlights contributions to quality of life, in line with innovation and sustainable development, whether in human, environmental, or economic terms.